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Oxo Diels–Alder reaction : ウィキペディア英語版
Oxo-Diels–Alder reaction
An oxo-Diels–Alder reaction is an organic reaction and a variation of the Diels–Alder reaction in which a suitable diene reacts with an aldehyde to form a dihydropyran ring. This reaction is of some importance to synthetic organic chemistry.
:
The oxo-DA reaction was first reported in 1949 〔''A Diels–Alder Type Reaction with Formaldehyde'' Thomas L. Gresham, Thomas R. Steadman J. Am. Chem. Soc., 1949, 71 (2), pp 737–738 〕 using a methylpentadiene and formaldehyde as reactants.
:
Asymmetric oxo-DA reactions (including catalytic reactions) are well known.〔''Tetrahedron Report number 869 Asymmetric hetero-Diels–Alder reactions of carbonyl compounds'' Helene Pellissier Tetrahedron 65 (2009) 2839–2877 〕 Many strategies rely on coordinating a chiral Lewis acid to the carbonyl group.
==See also==

* Aza Diels–Alder reaction

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